From: Astrologyweekly.com
"What will happen in 2012? Will the world end?"
Let us explore this question through a horary chart, genuine question asked by myself on June 27, 2009, at 10:20 pm CED, (location 01e37, 50n43): after doing some reading on the subject, I wanted to find the answer (or an answer) by horary.
Stunning chart! As the whole 2012 issue is a based on a calendar prediction, no wonder that the Ascendant ruler is Saturn, the master of Time. Notice the tight conjunction with the Moon (at the end of a Moon-Saturn cycle) in the 8th house (of transformation). A very clearly astrological picture of the humanity (the Moon) reaching at the end of some human calendar.
So, this is what we knew already, it's part of the question. Let us explore the chart indications.
First of all, looking around for more indication, I notice that Ceres is located right between the Moon and Saturn. Ceres is an asteroid known to be associated with 
Mother Earth (also food and ecology). Ceres is also applying to conjunct Saturn, in what represents the end of a Ceres-Saturn cycle (fyi, this is a 6 year long cycle). So, symbolically there is also a end to a time cycle on Mother Earth.
To those fearing a physical end of the Earth, I point out the MC-IC axis in this chart at the 15th degree in a fixed sign, with both 4th and 10th house rulers in a fixed sign: the physical and social environement will not suffer sudden changes.
Also, notice the position of the main significator, Saturn and the co-significator, the Moon, in succeedent houses: also an argument of continuity.
So the keyword cannot be sudden change, nor end, but rather transition.